Advancing mobile health interventions
Technology has created unprecedented opportunities to increase the reach and impact of healthcare with digital interventions. Digital technologies can also collect rich and granular data about a person’s state and context and leverage this information to adapt interventions to the rapidly changing needs of individuals in real-time, in their daily lives.
Despite the increasing use and appeal of digital interventions, a major gap exists between the growing technological capabilities for delivering them and research on the development and evaluation of these interventions.
Our team is developing new intervention frameworks and experimental designs that help investigators leverage advanced digital technologies to construct powerful interventions.

Just-in-Time Adaptive Interventions
A Just-in-Time Adaptive Intervention (JITAI) is a digital intervention delivery framework that guides how rapidly changing information about the person’s state and context should be used in practice to decide whether and how to intervene in real-time, in everyday life. JITAIs typically guide the adaptation of digital components on relatively fast timescales, typically every few days, hours or minutes.
EXAMPLE. A JITAI decision rule protocolizes an intervention for cigarette smoking. Learn more about this JITAI.
Micro-Randomized Trials for Optimizing JITAIs
When developing a Just-in-Time Adaptive Intervention, investigators often have scientific questions about how to best deliver and adapt momentary interventions in the real world. A Micro-Randomized Trial (MRT) helps investigators answer these questions. The MRT is a randomized trial that includes rapid sequential randomizations. This means that the same person may be repeatedly randomized to intervention options hundreds or thousands of times during a trial.

EXAMPLE. In the mobile assistance for regulating smoking (MARS) micro-randomized trial, a survey is delivered six times per day. Following the survey, participants are randomized to one of three intervention options. Learn more about MARS.
EXAMPLE. In the mobile assistance for regulating smoking (MARS) micro-randomized trial, a survey is delivered six times per day. Following the survey, participants are randomized to one of three intervention options. Learn more about MARS.

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